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Breast Cancer Research: Change Starts With You

Living with ER+ HER2- advanced breast cancer? If your cancer returned during or shortly after hormone therapy, a research study may be an option for you.

What is ER+ HER2- Breast Cancer?

ER+ HER2- is a type of breast cancer that uses a hormone called estrogen to grow. Additionally, the HER2 protein can act like a supercharger for cancer, making it grow and spread faster. Since ER+ HER2- breast cancer doesn't have HER2 proteins (which is why you see a negative sign at the end of the name), it might not be as aggressive. Knowing this helps doctors choose the right treatment for you.

Don’t know your breast cancer type? While we are looking for individuals with this specific type of advanced breast cancer, many factors can affect your eligibility. The study team will screen you for your breast cancer type, so don't let it stop you from learning more.

How is ER+ HER2- Breast Cancer Treated?

While HER2+ breast cancers can be treated with drugs targeting this protein, ER+ HER2- breast cancers are typically managed with hormone therapies that either help to lower the amount of estrogen in your body or block them from working.

Clinical Study Information

pionERA Breast Cancer Study

This study is designed to test an oral medication (taken by mouth) for advanced breast cancer. The study will compare this new medication to an existing treatment.*

You may be able to join this study if:

If this sounds like you, and you’re interested in participating, complete this quick form today!

*Both study drugs will be combined with another type of cancer medicine.

Why Your Participation Matters

People of color are underrepresented in clinical research. This is a problem because it means we don't fully understand how new and existing treatments work for different people.

By participating in research, you can help make sure that future treatments are safe and effective for everyone. Your perspective matters!

Join the NOWINCLUDED Cancer Circle!

The NOWINCLUDED cancer community is here to support you in making better-informed health decisions. If you’re not already a member, join today! It’s free.

As a member you gain:

  • Access to health experts and resources created just for you
  • Connection with people who may share your lived experiences
  • A platform to share your story and hear other people’s health stories
  • Early access to local and virtual events that may interest you
  • Information regarding research opportunities that may help you

Our Mission

Together, we can make healthcare more inclusive and ensure that everyone has the opportunity for better health. Data from this study will be used to develop safe and effective treatments for advanced breast cancer.